Just like the opening week, matchday two also kicks off on Friday as Nottingham Forest host Sheffield United.
Both sides were on the losing side in the first weekend and will be looking to get their first points on board.
It’s a busy Saturday as Liverpool welcome Bournemouth, Manchester United travel away to Tottenham Hotspur with the final fixture of the day between Manchester City and Newcastle.
Chelsea face West Ham in a London derby on Sunday as Arsenal travel to Crystal Palace on Monday.
Find below the BestBet’s predicitons of this weekend’s games: